« Back
Home /
IL-10 Recombinant Protein

IL-10 Recombinant Protein

Manufacturer	ProSci
Category	Neuroscience Neuroinflammation Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Immunostaining
Type	Proteins Recombinant
Specific against	other
Format	Lyophilized
Amount	10 ug
Item no.	PRS-90-555-10ug
eClass 6.1	34160400
eClass 9.0	42020190
Available
Applications	This recombinant proteins is for research use only.
Applications	This recombinant proteins is for research use only.
Buffer	Lyophilized from 0.2μm-filtered solution in 20mM Tris, 20mM NaCl, pH8.7.
Storage Conditions	Stable for at least 1 year after receipt when stored at -80˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Predicted Molecular Weight	~18kDa (SDS-PAGE)
Purity	≥95% (SDS-PAGE). Endotoxin level is less than <0.01EU/μg protein (LAL test; Lonza).
Background	Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.
Concentration	0.1mg/ml
Accession #	NP_000563.1
Ncbi Gene Id #	3586
Ncbi Official Symbol	IL10
Ncbi Official Full Name	interleukin 10
Ncbi Organism	Homo sapiens
Sequence	Human IL-10 (aa 19-178) with a N-terminal Met.
Biological Activity	Immobilized human IL-10 at 10ug/ml (100ul/well) can bind Cynomolgus IL-10RA-Fc. The EC50 of Cynomolgus IL-10RA-Fc is 0.24-0.56ug/ml.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 10 ug

available

Delivery expected until 6/6/2024