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Autophagy protein 5 Recombinant Protein

ArtNr PRS-92-187-0.05mg
Hersteller ProSci
Menge 0.05 mg
Kategorie
Typ Proteins Recombinant
Format Liquid
Specific against other
Konjugat/Tag Tag Free
Purity Greater than 95% as determined by reducing SDS-PAGE.<br />Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Dry ice Yes
Sequence Met1-Asp275
NCBI ATG5
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Autophagy protein 5,APG5-like,Apoptosis-specific protein,APG5L,ASP,ATG5
Versandbedingung Trockeneis
Lieferbar
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Dry Ice
Storage Conditions
Store at -20˚ C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Molecular Weight
32.4 kD
Background
ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.
By Type
Autophagy, Homeostasis, Innate Immunity, Signal Transduction
Protein Gi #
530379522
Buffer
Supplied as a 0.2 um filtered solution of 20mM Tris, 0.2M NaCl, 1mM DTT, 40%glycerol, pH 8.0 . It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Application Note
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
autophagy related 5
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species
Human
By Species
Human

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.05 mg
Lieferbar: In stock
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