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Autophagy protein 5 Recombinant Protein

Autophagy protein 5 Recombinant Protein

Item no.	PRS-92-187-0.05mg
Manufacturer	ProSci
Amount	0.05 mg
Category	Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Autophagy Cardiovascular Research Ischemia & Reperfusion Injury
Type	Proteins Recombinant
Format	Liquid
Specific against	other
Conjugate/Tag	Tag Free
Purity	Greater than 95% as determined by reducing SDS-PAGE.<br />Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Dry ice	Yes
Sequence	Met1-Asp275
NCBI	ATG5
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Autophagy protein 5,APG5-like,Apoptosis-specific protein,APG5L,ASP,ATG5
Shipping Condition	Dry ice
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Dry Ice
Storage Conditions	Store at -20˚ C, stable for 6 months after receipt. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Molecular Weight	32.4 kD
Background	ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.
By Type	Autophagy, Homeostasis, Innate Immunity, Signal Transduction
Protein Gi #	530379522
Buffer	Supplied as a 0.2 um filtered solution of 20mM Tris, 0.2M NaCl, 1mM DTT, 40%glycerol, pH 8.0 . It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Application Note	This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name	autophagy related 5
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Human
By Species	Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.05 mg

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Delivery expected until 1/1/2026

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