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BCL2L1 Recombinant Protein

BCL2L1 Recombinant Protein

ArtNr	PRS-96-056-0.1mg
Hersteller	ProSci
Menge	0.1 mg
Kategorie	Oncology By Cell Type Carcinoma Hematology Leukemia Lymphoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Apoptosis Western Blot By Organ Colorectal Cancer Testicular & Prostate Cancer
Typ	Proteins Recombinant
Format	Lyophilized
Applikationen	WB
Specific against	other
Konjugat/Tag	HIS
Purity	>92% as determined by SDS-PAGE.
Sequence	Met 1 - Arg 212
Citations	Terrano D.T., et al., 2010, Mol. Cell. Biol. 30:640-656. Wang J., et al., 2011, Cell. Signal. 23:2030-2038.
NCBI	BCL2L1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	BCL2L1,Bcl-XL,Bcl2-L-1,BCL-XL/S,BCL2L,BCLX,BCLXL,BCLXS,Bcl-X,bcl-xS
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Room Temp
Storage Conditions	Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight	24.6 kDa
Biological Activity	Measured by its binding ability in a functional ELISA. Immobilized human BID protein at 10μ g/ml (100μ l/well) can bind biotinylated human BCL2L1 protein, The EC50 of biotinylated human BCL2L1 is 6. 5 ng/mL.
Background	Bcl-2-like protein 1 (BCL2L1), is also known as Apoptosis regulator Bcl-X (Bcl-XL). BCL2L1 / Bcl-XL is a homodimer protein and belongs to the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a potent inhibitor of cell death. BCL2L1 Inhibits activation of caspases. BCL2L1 appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. BCL2L1 / Bcl-XL also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.
By Type	Apoptosis, Cancer
Buffer	20mM HEPES, 50mM KCl, pH 7.5
Application Note	This recombinant protein can be used for WB. For research use only.
NCBI Official Name	BCL2-like 1
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Human
By Species	Human

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.1 mg

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Lieferung vsl. bis 04.12.2025

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