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PLAU Recombinant Protein

ArtNr PRS-96-630-0.05mg
Hersteller ProSci
Menge 0.05 mg
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Applikationen WB
Specific against other
Konjugat/Tag HIS
Purity >95% as determined by SDS-PAGE.
Sequence Ser 21 - Leu 431
Citations Nagai M., et al., 1985, Gene 36:183.
Jacobs P., et al., 1985, DNA 4:139.
Harbeck, N. et al., 2002, Clin. Breast Cancer 3:196.
NCBI PLAU
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Urokinase, PLAU, ATF, UPA, URK, u-PA,BDPLT5,QPD
Lieferbar
Manufacturer - Applications
This recombinant protein can be used for WB. For research use only.
Storage Conditions
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
45 kDa
Biological Activity
Measured by its ability to bind human PLAUR in a function ELISA.
Background
Urokinase - type plasminogen activator is also known as PLAU and UPA, a serine protease with an extremely limited substrate specificity, cleaving the sequence Cys – Pro – Gly - Arg560 - Val561 – Val – Gly – Gly – Cys in plasminogen to form plasmin. uPA is a potent marker of invasion and metastasis in a variety of human cancers associated with breast, stomach, colon, bladder, ovary, brain and endometrium.uPA and its receptor (uPAR) have been implicated in a broad spectrum of pathophysiological processes, including fibrinolysis, proteolysis, inflammation, atherogenesis and plaque destabilization, all of which are involved in the pathogenesis of MI (myocardial infarction).
Buffer
50 mM NaAc, 100 mM NaCl, pH5.0
NCBI Official Name
plasminogen activator, urokinase
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.05 mg
Lieferbar: In stock
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