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Bone proteoglycan II Recombinant Protein

ArtNr PRS-96-234-0.2mg
Hersteller ProSci
Menge 0.2 mg
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Applikationen WB
Specific against other
Konjugat/Tag HIS
Purity >90% as determined by SDS-PAGE.<br><br>Endotoxin level is less than 1.0 EU per ug by the LAL method.
Sequence Gly 17 - Lys 359
Citations Santra, Manoranjan, et al., 2002, J. Biol. Chem. (United States) 277 (38): 35671–81.
Iozzo, R V., et al., 1999, J. Biol. Chem. (UNITED STATES) 274 (8): 4489–92.
Schönherr, E., et al., 1998, Arch. Biochem. Biophys. (UNITED STATES) 355 (2): 241–8.
Takeuchi, Y., et al., 1994, J. Biol. Chem. (UNITED STATES) 269 (51): 32634–8.
NCBI DCN
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Decorin,DCN,CSCD,DSPG2,PG40,PGII,PGS2,SLRR1B
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight
38.8 kDa
Biological Activity
Measured by its ability to modulate collagen fibrillogenesis. At 5 μ g/mL, rhDecorin can significantly delay the rate of type I collagen fibrillogenesis.
Background
Decorin is also known as bone proteoglycan II, PGS2, SLRR1B, DCN, DSPG2 and PG40, is a secreted chondroitin /dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. Decorin and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. Decorin appears to influence fibrillogenesis, and also interacts with fibronectin, thrombospondin, the complement component C1q, epidermal growth factor receptor (EGFR) and transforming growth factor-beta (TGF-beta). Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD).
By Type
Signal Transduction
Buffer
PBS, pH7.4
Application Note
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
decorin
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species
Human
By Species
Human

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.2 mg
Lieferbar: In stock
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