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Bone proteoglycan II Recombinant Protein

Bone proteoglycan II Recombinant Protein

Item no.	PRS-96-234-0.2mg
Manufacturer	ProSci
Amount	0.2 mg
Category	Oncology Neuroscience Neural Signaling Peptides & Proteins Recombinant Proteins Western Blot By Organ Bladder Cancer
Type	Proteins Recombinant
Format	Lyophilized
Applications	WB
Specific against	other
Conjugate/Tag	HIS
Purity	>90% as determined by SDS-PAGE.<br><br>Endotoxin level is less than 1.0 EU per ug by the LAL method.
Sequence	Gly 17 - Lys 359
Citations	Santra, Manoranjan, et al., 2002, J. Biol. Chem. (United States) 277 (38): 35671–81. Iozzo, R V., et al., 1999, J. Biol. Chem. (UNITED STATES) 274 (8): 4489–92. Schönherr, E., et al., 1998, Arch. Biochem. Biophys. (UNITED STATES) 355 (2): 241–8. Takeuchi, Y., et al., 1994, J. Biol. Chem. (UNITED STATES) 269 (51): 32634–8.
NCBI	DCN
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Decorin,DCN,CSCD,DSPG2,PG40,PGII,PGS2,SLRR1B
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Room Temp
Storage Conditions	Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight	38.8 kDa
Biological Activity	Measured by its ability to modulate collagen fibrillogenesis. At 5 μ g/mL, rhDecorin can significantly delay the rate of type I collagen fibrillogenesis.
Background	Decorin is also known as bone proteoglycan II, PGS2, SLRR1B, DCN, DSPG2 and PG40, is a secreted chondroitin /dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. Decorin and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. Decorin appears to influence fibrillogenesis, and also interacts with fibronectin, thrombospondin, the complement component C1q, epidermal growth factor receptor (EGFR) and transforming growth factor-beta (TGF-beta). Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD).
By Type	Signal Transduction
Buffer	PBS, pH7.4
Application Note	This recombinant protein can be used for WB. For research use only.
NCBI Official Name	decorin
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Human
By Species	Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.2 mg

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Delivery expected until 2/5/2026

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