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ST2 Recombinant Protein

ArtNr PRS-96-428-0.2mg
Hersteller ProSci
Menge 0.2 mg
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Applikationen WB
Specific against other
Konjugat/Tag Fc
Purity >95% as determined by SDS-PAGE.<br><br>Endotoxin level is less than 1.0 EU per ug by the LAL method.
Sequence Lys 19 - Pro 323
Citations Tago K., et al., 2001, Biochem. Biophys. Res. Commun. 285:1377-1383.
Schmitz J., et al., 2005, Immunity 23:479-490.
NCBI IL1RL1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL1RL1, DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1
Lieferbar
Manufacturer - Applications
This recombinant protein can be used for WB. For research use only.
Manufacturer - Conjugate / Tag
C-Fc Tag
Storage Conditions
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
61.0 kDa
Biological Activity
Measured by its binding ability in a functional ELISA. Immobilized recombinant human IL33 at 10μg/ml (100μl/well) can bind rh IL1RL1 /ST2 Fc Chimera with a linear range of 0. 3-5μg/ml.
Background
Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.
Buffer
Tris with Glycine,  Arginine and NaCl,  pH7.5
NCBI Official Name
interleukin 1 receptor-like 1
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.2 mg
Lieferbar: In stock
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