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ST2 Recombinant Protein

ST2 Recombinant Protein

Item no.	PRS-96-428-0.2mg
Manufacturer	ProSci
Amount	0.2 mg
Category	Neuroscience Neural Lineage Markers Neuroinflammation Molecular Targets for Neuroscience Neural Signaling Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Western Blot Glial Cell Markers
Type	Proteins Recombinant
Format	Lyophilized
Applications	WB
Specific against	other
Conjugate/Tag	Fc
Purity	>95% as determined by SDS-PAGE.<br><br>Endotoxin level is less than 1.0 EU per ug by the LAL method.
Sequence	Lys 19 - Pro 323
Citations	Tago K., et al., 2001, Biochem. Biophys. Res. Commun. 285:1377-1383. Schmitz J., et al., 2005, Immunity 23:479-490.
NCBI	IL1RL1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IL1RL1,DER4,FIT-1,IL33R,ST2,ST2L,ST2V,T1
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Manufacturer - Conjugate / Tag	C-Fc Tag
Shipping Temperature	Room Temp
Storage Conditions	Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight	61.0 kDa
Biological Activity	Measured by its binding ability in a functional ELISA. Immobilized recombinant human IL33 at 10μ g/ml (100μ l/well) can bind rh IL1RL1 /ST2 Fc Chimera with a linear range of 0. 3-5μ g/ml.
Background	Interleukin 1 receptor-like 1 (IL1RL1) is also known as ST2, DER4, FIT-1, IL33R, ST2L, ST2V, which belongs to the interleukin-1 receptor family. IL1RL1 contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RL1 is receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 possibly involved in helper T-cell function. IL1RL1 can interact with MYD88, IRAK1, IRAK4, and TRAF6.
By Type	Innate Immunity
Buffer	Tris with Glycine, Arginine and NaCl, pH7.5
Application Note	This recombinant protein can be used for WB. For research use only.
NCBI Official Name	interleukin 1 receptor-like 1
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Human
By Species	Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.2 mg

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Delivery expected until 11/6/2025

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