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Interleukin 6 Recombinant Protein (HEK293 Expressed)

ArtNr PRS-96-446-0.02mg
Hersteller ProSci
Menge 0.02 mg
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Applikationen WB
Specific against other
Konjugat/Tag Tag Free
Purity >98% as determined by SDS-PAGE.
Sequence Val 30 - Met 212
Citations Ferguson-Smith AC,et.al. 1988, Genomics 2 (3): 203–8.
Schwantner A,et. al. 2004, J. Biol. Chem. 279 (1): 571–6.
Schuster B,et. al. 2003, J. Biol. Chem. 278 (11): 9528–35.
Taga T,et al.1989, Cell 58 (3): 573–81.
NCBI IL6
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias IL6,HGF,Interleukin-6,BSF2,HSF,IFNB2
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight
20.8 kDa
Biological Activity
Immobilized Human IL-6, Tag Free at 5ug/mL (100uL/well) can bind Biotinylated Human IL-6 R alpha, His Tag with a linear range of 4-125 ng/mL.
Background
Interleukin 6 (IL-6) is also known as HGF, BSF2, HSF, IFNB2 and IL-6, originally identified as a B cell differentiation factor, is a multifunctional cytokine that regulates immune responses, hematopoiesis, acute phase responses, and inflammatory reactions.It is secreted by T cells, macrophages , monocytes, fibroblasts, endothelial cells, et.al. to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein. IL-6 is relevant to many disease processes such as diabetes, atherosclerosis, depression, Alzheimer's Disease, systemic, lupus erythematosus, prostate cancer and rheumatoid arthritis. Advanced/metastatic cancer patients have higher levels of IL-6 in their blood.Hence there is an interest in developing anti-IL-6 agents as therapy against many of these diseases.
By Type
Cancer, Chemokines & Cytokines, Immunology, Neuroscience, Obesity, Signal Transduction
Buffer
PBS, pH7.4
Application Note
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
interleukin 6 (interferon, beta 2)
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species
Human
By Species
Human

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.02 mg
Lieferbar: In stock
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Lieferung vsl. bis 06.11.2025 

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