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M-CSF Recombinant Protein

ArtNr PRS-96-923-0.05mg
Hersteller ProSci
Menge 0.05 mg
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Applikationen WB, ELISA
Specific against other
Konjugat/Tag HIS
Purity >95% as determined by SDS-PAGE.<br><br>Endotoxin level is less than 1.0 EU per ug by the LAL method.
Sequence Glu 33 - Arg 255
Citations Sapi E., 2004, Exp. Biol. Med., 229 : 1-11.
Jang Mei-Huei, 2006, The Journal of Immunology, 177 (6): 4055-4063.
Cao, Qi, 2014, Kidney International, 85 (4): 794-806.
NCBI M-CSF
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias M-CSF,CSF-1,Lanimostim
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight
26 kDa
Biological Activity
Measured by its binding ability in a functional ELISA. Immobilized Human M-CSF, His Tag at 5 ug/mL (100 uL/well) can bind Human M-CSF R, Fc Tag with a linear range of 0.17-1.52 ng/mL.
Background
The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which influences hematopoietic stem cells to differentiate into macrophages or other related cell types. Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection. It is one of the three experimentally described colony-stimulating factors. M-CSF binds to the colony stimulating factor 1 receptor. Macrophage colony-stimulating factor has been shown to interact with PIK3R2. M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. Locally produced M-CSF in the vessel wall contributes to the development and progression of atherosclerosis.
By Type
Chemokines & Cytokines, Growth Factors
Buffer
PBS, pH7.4
Application Note
This recombinant protein can be used for E, WB. For research use only.
NCBI Official Name
Colony stimulating factor 1 (macrophage)
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species
Human
By Species
Human

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.05 mg
Lieferbar: In stock
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