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M-CSF Recombinant Protein

M-CSF Recombinant Protein

Item no.	PRS-96-923-0.05mg
Manufacturer	ProSci
Amount	0.05 mg
Category	Oncology Neuroscience Neuroinflammation By Cell Type Carcinoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Mesothelioma Western Blot ELISA By Organ Colorectal Cancer
Type	Proteins Recombinant
Format	Lyophilized
Applications	WB, ELISA
Specific against	other
Conjugate/Tag	HIS
Purity	>95% as determined by SDS-PAGE.<br><br>Endotoxin level is less than 1.0 EU per ug by the LAL method.
Sequence	Glu 33 - Arg 255
Citations	Sapi E., 2004, Exp. Biol. Med., 229 : 1-11. Jang Mei-Huei, 2006, The Journal of Immunology, 177 (6): 4055-4063. Cao, Qi, 2014, Kidney International, 85 (4): 794-806.
NCBI	M-CSF
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	M-CSF,CSF-1,Lanimostim
Shipping Condition	Room temperature
Available
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Room Temp
Storage Conditions	Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight	26 kDa
Biological Activity	Measured by its binding ability in a functional ELISA. Immobilized Human M-CSF, His Tag at 5 ug/mL (100 uL/well) can bind Human M-CSF R, Fc Tag with a linear range of 0.17-1.52 ng/mL.
Background	The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which influences hematopoietic stem cells to differentiate into macrophages or other related cell types. Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection. It is one of the three experimentally described colony-stimulating factors. M-CSF binds to the colony stimulating factor 1 receptor. Macrophage colony-stimulating factor has been shown to interact with PIK3R2. M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. Locally produced M-CSF in the vessel wall contributes to the development and progression of atherosclerosis.
By Type	Chemokines & Cytokines, Growth Factors
Buffer	PBS, pH7.4
Application Note	This recombinant protein can be used for E, WB. For research use only.
NCBI Official Name	Colony stimulating factor 1 (macrophage)
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species	Human
By Species	Human

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.05 mg

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Delivery expected until 12/4/2025

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