ArtNr |
PVG-C5253-1mg |
Hersteller |
ACROBiosystems
|
Menge |
1 mg |
Quantity options |
100 ug
1 mg
|
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Powder |
Specific against |
Monkey (Cynomolgus, Simian) |
Host |
HEK293 |
Isotype |
IgG2a |
Konjugat/Tag |
Unconjugated, C-mFc |
Purity |
95% |
NCBI |
XP_005549281.1 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
C7orf15,C7orf15MGC138295,CD112R,MGC104322,MGC138297,MGC2463,PVRIG,CD112 receptor |
Versandbedingung |
Raumtemperatur |
Lieferbar |
|
Specificity |
Cynomolgus |
Manufacturer - Category |
Protein / Immune Checkpoint Proteins |
Manufacturer - Conjugate / Tag |
Unconjugated, C-mFc(mIgG2a) |
Manufacturer - Species |
Cynomolgus |
Shipping Temperature |
RT |
Storage Conditions |
-20°C |
Molecular Weight |
40.7 kDa |
Description |
Cynomolgus PVRIG, Mouse IgG2a Fc Tag (PVG-C5253) is expressed from human 293 cells (HEK293). It contains AA Thr 41 - Asp 171 (Accession # A0A2K5WVV8-1). |
Background |
Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. |
Molecule |
PVRIG |
Exp Region |
Thr 41 - Asp 171 |
Characteristics |
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 40.7 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin |
0.1 EU per μg |
Buffer |
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5 |
Stability |
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution.For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Protectant |
trehalose |
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