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Cynomolgus PVRIG Protein, Mouse IgG2a Fc Tag (MALS verified) Europäischer Partner

ArtNr PVG-C5253-1mg
Hersteller ACROBiosystems
Menge 1 mg
Quantity options 100 ug 1 mg
Kategorie
Typ Proteins Recombinant
Format Powder
Specific against Monkey (Cynomolgus, Simian)
Host HEK293
Isotype IgG2a
Konjugat/Tag Unconjugated, C-mFc
Purity 95%
NCBI XP_005549281.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias C7orf15,C7orf15MGC138295,CD112R,MGC104322,MGC138297,MGC2463,PVRIG,CD112 receptor
Versandbedingung Raumtemperatur
Lieferbar
Specificity Cynomolgus
Manufacturer - Category
Protein / Immune Checkpoint Proteins
Manufacturer - Conjugate / Tag
Unconjugated, C-mFc(mIgG2a)
Manufacturer - Species
Cynomolgus
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
40.7 kDa
Description
Cynomolgus PVRIG, Mouse IgG2a Fc Tag (PVG-C5253) is expressed from human 293 cells (HEK293). It contains AA Thr 41 - Asp 171 (Accession # A0A2K5WVV8-1).
Background
Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
Molecule
PVRIG
Exp Region
Thr 41 - Asp 171
Characteristics
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 40.7 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
0.1 EU per μg
Buffer
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution.For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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