ArtNr |
RP02211-1000ug |
Hersteller |
Abclonal
|
Menge |
1000 ug |
Quantity options |
1000 ug
100 ug
500 ug
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
Human (Homo sapiens) |
Host |
Human |
Purity |
> 95% as determined by Tris-Bis PAGE.> 95% as determined by HPLC. |
NCBI |
GFRAL |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
GFR alpha-like,GFRAL,GRAL,C6orf144 |
Versandbedingung |
Gekühlt |
Lieferbar |
|
Manufacturer - Applications |
< 1EU per μg by the LAL method. |
Manufacturer - Category |
Proteins |
Shipping Temperature |
ice pack |
Storage Conditions |
Store at -20°C.Store the lyophilized protein at -20°C to -80°C up to 1 year from the date of receipt. |After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week. |
Protein Weight |
40.7 kDa |
Description |
Recombinant Human GFR alpha-like/GFRAL Protein is produced by mammalian expression system. The target protein is expressed with sequence (Ser19-Glu351) of Human GFR alpha-like/GFRAL (Accession #) fused with a His and Avi tag at the C-terminal. . |
Background |
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses |
Manufacturer - Cross Reactivity |
Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
Immunogen |
Ser19-Glu351 |
Route |
C-His&Avi |
Manufacturer - Research Area |
Growth Factor |
Protein Formulation |
Lyophilized from 0.22um filtered solution in 20mM PB, 300mM NaCl (pH 6.5). Normally 5 % trehalose is added as protectant before lyophilization. |
Expected Protein Size |
40.7 kDa |
Gene Symbol |
GFRAL |
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