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Mouse Transferrin R2 Protein, mouse IgG1 Fc Tag, low endotoxin

Mouse Transferrin R2 Protein, mouse IgG1 Fc Tag, low endotoxin

ArtNr	TF2-M5269-1mg
Hersteller	ACROBiosystems
Menge	200 ug x 5
Quantity options	200 ug x 5 50 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solid
Specific against	Mouse (Murine, Mus musculus)
Host	HEK293
Isotype	IgG1
Konjugat/Tag	Unconjugated, N-mFc
Purity	95%
Citations	(1) Kawabata H., et al., 2001, Blood 98:1949-1954.
NCBI	NP_056614.3
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Transferrin R2,TFR2
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	N-mFc(mIgG1), Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	101.1 kDa
Manufacturer - Format	Powder
Description	Transferrin receptor protein 2 (TFR2) is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. The mutations in TFR2 gene have been associated with hereditary hemochromatosis type III. Furthermore, TFR2 is involved in the uptake of transferrin-bound iron into cells by endocytosis, although its role is minor compared to transferrin receptor 1.
Background	Transferrin receptor protein 2 (TFR2) is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. The mutations in TFR2 gene have been associated with hereditary hemochromatosis type III. Furthermore, TFR2 is involved in the uptake of transferrin-bound iron into cells by endocytosis, although its role is minor compared to transferrin receptor 1.
Molecule	Transferrin R2
Exp Region	Arg 103 - Phe 798
Characteristics	This protein carries a mouse IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 101.1 kDa. The protein migrates as 116 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	0.1 EU per μg
Buffer	Tris with Glycine, Arginine and NaCl, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

TF2-M5269-1mg-datasheet.pdf

TF2-M5269-1mg-safety-datasheet.pdf