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Biotinylated Human Latent TGF-beta 3 / Latent TGFB3 Protein, His,Avitag™

Biotinylated Human Latent TGF-beta 3 / Latent TGFB3 Protein, His,Avitag™

ArtNr	TG3-H82E6-100ug
Hersteller	ACROBiosystems
Menge	100 ug
Quantity options	100 ug 200 ug 20 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Biotin, Avi
Purity	90%
NCBI	NP_003230.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	TGFB3,ARVD,TGF-beta3
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	N-10xHis & C-Avi, Biotin-labeled
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	48.4 kDa
Manufacturer - Format	Powder
Description	Transforming growth factor beta 3 ( TGFB3) is also known as TGF-β3, is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development. TGF-beta 3 is similar with TGF-beta 1 and -beta 2, act as cellular switches to regulate immune function, cell proliferation, and epithelial-mesenchymal transition. TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3. Once activated following release of LAP, TGF-beta-3 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal.
Background	Transforming growth factor beta 3 ( TGFB3) is also known as TGF-β3, is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development. TGF-beta 3 is similar with TGF-beta 1 and -beta 2, act as cellular switches to regulate immune function, cell proliferation, and epithelial-mesenchymal transition. TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3. Once activated following release of LAP, TGF-beta-3 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal.
Molecule	TGF-beta 3
Exp Region	Leu 24 - Ser 412
Characteristics	This protein carries a polyhistidine tag at the N-terminus and an Avi tag (Avitag™) at the C-terminus. The protein has a calculated MW of 48.4 kDa. The protein migrates as 15 kDa, 40-45 kDa and 60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

TG3-H82E6-100ug-datasheet.pdf

TG3-H82E6-100ug-safety-datasheet.pdf