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SARS-CoV-2 Spike protein (S1, T95I, G142D, E154K, L452R, E484Q, D614G, P681R, His Tag) Europäischer Partner

ArtNr Z03611-100
Hersteller GenScript
Menge 100 ug
Quantity options 1 mg 100 ug
Kategorie
Typ Proteins
Specific against SARS-CoV-2
Host CHO cells
Purity > 90% as analyzed by SDS-PAGE
Dry ice Yes
Citations 1. Emergence of a novel SARS-CoV-2 strain in Southern California, USA.2. New California Variant May Be Driving Virus Surge There, Study Suggests.3. Neutralization of SARS-CoV-2 Variants B.1.429 and B.1.351.4. Tracking SARS-CoV-2 variants.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Lineage B.1.617.1; variant Kappa; VUI-21APR-01
Lieferbar
Country of Origin
USA
Storage Conditions
Upon receiving, this product remains stable for up to 6 months at -20°C or below. Please avoid repeated freeze-thaw cycles.
Apparent Molecular Weight
~112 kDa, on SDS-PAGE under reducing conditions.
Theoretical Molecular Weight
75.7 kDa
Concentration
Please refer to the COA for the specific lot.
Formulation
Supplied as a solution in PBS, pH 7.4.
Endotoxin Level
< 0.2 EU/μg of protein by gel clotting method
Target Background
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. As of May 2021, three sublineages have been found. Despite its name, B.1.617.3 was the first sublineage of this variant to be detected, in October 2020 in India. This sublineage has remained relatively uncommon compared to the two other sublineages, B.1.617.1 (also known as variant Kappa) and B.1.617.2 (also known as variant Delta), both of which were first detected in December 2020. This variant has the double mutations E484Q and L452R in the spike proteins. Emerging research suggests the variant may be more transmissible than previously evolved ones. Whether the effectiveness of currently-deployed vaccines is affected remains under investigation. Moreover, the sublineage B.1.617.2 has been redesignated as "variant of concern" (VOC-21APR-02) in May 2021, which spreads more quickly than the original version of the virus.
Biological Activity
This protein is validated to bind with human ACE2 in functional ELISA assay.
Protein Construction
Expressed with the mutations of T95I, G142D, E154K, L452R, E484Q, D614G, P681R. S1 protein (Gln14-Arg685)Accession # P0DTC2 Poly-His N-term C-term

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 24.07.2025 

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