BCL2L1 Antibody

ArtNr	PRS-13-079-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Cell Biology Cell Status Apoptosis Immunoprecipitation Western Blot Immunofluorescence Autophagy Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF, IP
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	BCL2L1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Bcl-xL Antibody: BCLX,BCL2L,BCLXL,BCLXS,Bcl-X,bcl-xL,bcl-xS,PPP1R52,BCL-XL/S,BCLX,Bcl-2-like protein 1,Apoptosis regulator Bcl-X,Bcl2-L-1
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 30kDa
Manufacturer - Research Area	Apoptosis, Autophagy, Cancer, Cell Cycle, Immunology, Neuroscience
Background	The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
By Type	Apoptosis, Autophagy, Cancer, Cell Cycle, Immunology, Neuroscience
Modifications	None
Purification	Affinity purification
Positive Control 1	HT-29
Positive Control 2	B-cell
Positive Control 3	A-549
Positive Control 4	SW480
Positive Control 5	BT-474
Positive Control 6	K-562
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IF: 1:50 - 1:200 IP: 1:50 - 1:100
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human BCL2L1 (NP_612815.1).
Clonality	Polyclonal
NCBI Official Name	BCL2-like 1
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 100 uL

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Lieferung vsl. bis 06.11.2025

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