IGF1R Antibody

ArtNr	PRS-13-102-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Oncology Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies By Cell Type Blastoma Carcinoma Sarcoma Cell Biology Cell Culture Cytokines Immunohistochemistry Western Blot Immunofluorescence Endocrine Regulation of Lipid Metabolism Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	IGF1R
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	IGF1R,CD221 antigen,CD221,IGF1 Receptor,IGFR,IGF-I receptor,Soluble IGF1R variant 1,Soluble IGF1R variant 2,Type 1 IGF receptor,IGFIR,JTK13
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 90kDa/130kDa
Manufacturer - Research Area	Apoptosis, Cancer, Cell Cycle, Growth Factors, Immunology, Signal Transduction
Background	This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
By Type	Apoptosis, Cancer, Cell Cycle, Growth Factors, Immunology, Signal Transduction
Modifications	None
Purification	Affinity purification
Positive Control 1	293T
Positive Control 2	HepG2
Positive Control 3	A375
Positive Control 4	HeLa
Positive Control 5	MCF7
Positive Control 6	Mouse kidney
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IF: 1:50 - 1:200
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 660-760 of human IGF1R (NP_000866.1).
Clonality	Polyclonal
NCBI Official Name	insulin-like growth factor 1 receptor
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 100 uL

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Lieferung vsl. bis 06.11.2025

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