PRKCA Antibody

ArtNr	PRS-13-116-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Oncology Neuroscience Metabolism Diabetes Targets for Rodent Neurosciences Neural Signaling Antibodies By Cell Type Melanoma Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	PRKCA
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PRKCA,Aging-associated gene 6,AAG6,Alpha PKC,PKC-A,Pkcalpha,Protein kinase C alpha type,PKC Alpha,PKC-alpha,PKCA,Protein kinase c alpha,Protein kinase C,alpha
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 76kDa
Manufacturer - Research Area	Apoptosis, Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Background	Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
By Type	Apoptosis, Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Modifications	None
Purification	Affinity purification
Positive Control 1	Jurkat
Positive Control 2	K-562
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IF: 1:50 - 1:200
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 570 to the C-terminus of human PRKCA (NP_002728.1).
Clonality	Polyclonal
NCBI Official Name	protein kinase C, alpha
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 100 uL

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Lieferung vsl. bis 04.12.2025

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