PKN1 Antibody

ArtNr	PRS-13-202-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Targets for Rodent Neurosciences Aging & Neurological Disorders Neural Development Antibodies By Cell Type Carcinoma Immunohistochemistry Western Blot Primary Antibodies Progenitor Markers
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	PKN1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 120kDa
Manufacturer - Research Area	Signal Transduction
Background	The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
By Type	Signal Transduction
Modifications	None
Purification	Affinity purification
Positive Control 1	U-251MG
Positive Control 2	A-549
Positive Control 3	293T
Positive Control 4	HeLa
Positive Control 5	HepG2
Positive Control 6	HT-1080
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:1000 IHC: 1:50 - 1:100
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PKN1 (NP_002732.3).
Clonality	Polyclonal
NCBI Official Name	protein kinase N1
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.
Manufacturer - Additional Names	DBK, PAK-1, PAK1, PKN, PKN-ALPHA, PRK1, PRKCL1, serine/threonine-protein kinase N1, protease-activated kinase 1, protein kinase C-like 1, protein kinase C-like PKN, protein kinase C-related kinase 1, protein kinase PKN-alpha, serine-threonine kinase N, serine/threonine protein kinase N

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 uL

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Lieferung vsl. bis 04.12.2025

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