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TGFBR1 Antibody

ArtNr PRS-13-260-100uL
Hersteller ProSci
Menge 100 uL
Quantity options 100 uL
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB, IF, IHC
Specific against Human (Homo sapiens), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
NCBI TGFBR1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Versandbedingung Gekühlt
Lieferbar
Specificity Human,Rat
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight
Observed: 56kDa
Manufacturer - Research Area
Cancer, Cell Cycle, Growth Factors, Signal Transduction, Stem Cell
Background
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
By Type
Cancer, Cell Cycle, Growth Factors, Signal Transduction, Stem Cell
Modifications
None
Purification
Affinity purification
Positive Control 1
HepG2
Positive Control 2
HeLa
Positive Control 3
PC-3
Concentration
batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note
WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IF: 1:50 - 1:100
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 34-124 of human TGFBR1 (NP_001124388.1).
Clonality
Polyclonal
NCBI Official Name
transforming growth factor, beta receptor 1
NCBI Organism
Homo sapiens
User Note
Optimal dilutions for each application to be determined by the researcher.
Manufacturer - Additional Names
activin A receptor type II-like kinase, 53kD, TGF-beta type I receptor, TGF-beta receptor type-1, TGF-beta receptor type I, TGFR-1, SKR4, LDS2A, LDS1A, ALK5, ALK-5, ACVRLK4, AAT5, transforming growth factor, beta receptor 1, TGFBR1, transforming growth factor-beta receptor type I, beta receptor I (activin A receptor type II-like kinase, 53kD), transforming growth factor beta receptor I, tbetaR-I, serine/threonine-protein kinase receptor R4, activin receptor-like kinase 5, activin A receptor type II-like kinase, 53kDa

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
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