NACA Antibody

ArtNr	PRS-13-442-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Antibodies Immunohistochemistry Immunoprecipitation Western Blot Cardiovascular Research Hypertension Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IP, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	NACA
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	HSD48,NAC-alpha1,skNAC,NACA,nascent polypeptide-associated complex subunit alpha,alpha-NAC,muscle-specific form,nascent-polypeptide-associated complex alpha polypeptide
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 37kDa
Manufacturer - Research Area	Other
Background	This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes.
By Type	Other
Modifications	None
Purification	Affinity purification
Positive Control 1	HL-60
Positive Control 2	SW620
Positive Control 3	293T
Positive Control 4	U-87MG
Positive Control 5	HeLa
Positive Control 6	Mouse liver
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IHC: 1:50 - 1:100 IP: 1:50 - 1:100
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human NACA (NP_001106673.1).
Clonality	Polyclonal
NCBI Official Name	nascent polypeptide associated complex subunit alpha
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 100 uL

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Lieferung vsl. bis 06.11.2025

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