ADAMTS2 Antibody

Blue Ice

Observed: 120kDa

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase. This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

None

A375

THP-1

batch dependent

WB: 1:500 - 1:2000

Polyclonal

Mus musculus

ADAM-TS 2, ADAM-TS2, ADAMTS-2, PC I-NP, PCINP, pNPI, A disintegrin and metalloproteinase with thrombospondin motifs 2, a disintegrin and metalloproteinase with thrombospondin repeats, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2, procollagen I/II amino propeptide-processing enzyme, procollagen N-endopeptidase, procollagen N-proteinase