IDH3B Antibody

Blue Ice

Observed: 42kDa

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

None

NCI-H460

293T

Mouse heart

batch dependent

WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IF: 1:50 - 1:100

Polyclonal

Homo sapiens

isocitric dehydrogenase subunit beta, isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, beta subunit, isocitrate dehydrogenase [NAD] subunit beta, NAD+-specific isocitrate dehydrogenase beta, NAD+-specific isocitrate dehydrogenase b subunit, NAD+-specific ICDH, NAD(+)-specific ICDH subunit beta, RP46, MGC903, H-IDHB, FLJ11043, isocitrate dehydrogenase 3 (NAD+) beta, IDH3B