PKM Antibody

ArtNr	PRS-15-259-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Metabolism Glucose Homeostasis Antibodies Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	PKM
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PKM,p58,PK3,PKM2,Pyruvate Kinase,Pyruvate kinase 2/3,Pyruvate kinase,m1,Pyruvate kinase,muscle,TCB,Tumor M2-PK,OIP-3,OIP3,Opa-interacting protein 3,CTHBP,PK,muscle type,PK2,Pyruvate kinase isozymes M1/M2,Pyruvate kinase muscle isozyme,THBP1
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 65kDa
Manufacturer - Research Area	Cancer, Signal Transduction
Background	This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.
By Type	Cancer, Signal Transduction
Modifications	None
Purification	Affinity purification
Positive Control 1	U-251MG
Positive Control 2	LO2
Positive Control 3	HeLa
Positive Control 4	A-549
Positive Control 5	Mouse kidney
Positive Control 6	Mouse brain
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IF: 1:50 - 1:200
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 11-221 of human PKM (NP_002645.3).
Clonality	Polyclonal
NCBI Official Name	pyruvate kinase, muscle
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 100 uL

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Lieferung vsl. bis 05.02.2026

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