SMG7 Antibody

ArtNr	PRS-16-018-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Oncology Antibodies Western Blot Primary Antibodies By Organ Breast Cancer
Typ	Antibody Primary
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	SMG7
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	C1orf16,EST1C,SGA56M,protein SMG7,EST1 telomerase component homolog C,EST1-like protein C,breast cancer-associated antigen SGA-56M,ever shorter telomeres 1C,smg-7 homolog,nonsense mediated mRNA decay factor
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 127kDa
Manufacturer - Research Area	Other
Background	This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
By Type	Other
Modifications	None
Purification	Affinity purification
Positive Control 1	Jurkat
Positive Control 2	Mouse testis
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:200 - 1:2000
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SMG7 (NP_963863.2).
Clonality	Polyclonal
NCBI Official Name	SMG7 nonsense mediated mRNA decay factor
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 100 uL

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Lieferung vsl. bis 05.02.2026

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