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NTRK1 Antibody

ArtNr PRS-16-139-100uL
Hersteller ProSci
Menge 100 uL
Quantity options 100 uL
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
NCBI NTRK1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias NTRK1,Oncogene TRK,TrkA/NGF receptor,Tropomyosin-related kinase A,TRK,TRK1,Tyrosine kinase receptor,Tyrosine kinase receptor A,gp140trk,MTC,p140-TrkA,Trk-A,TRKA
Versandbedingung Gekühlt
Lieferbar
Specificity Human,Mouse,Rat
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight
Observed: 140kDa
Manufacturer - Research Area
Cancer, Cell Cycle, Growth Factors, Neuroscience, Signal Transduction
Background
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
By Type
Cancer, Cell Cycle, Growth Factors, Neuroscience, Signal Transduction
Modifications
None
Purification
Affinity purification
Positive Control 1
Mouse brain
Positive Control 2
Rat brain
Concentration
batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 700 to the C-terminus of human NTRK1 (NP_002520.2).
Clonality
Polyclonal
NCBI Official Name
neurotrophic tyrosine kinase, receptor, type 1
NCBI Organism
Homo sapiens
User Note
Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
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