Vergleich

THRB Antibody

ArtNr PRS-16-254-100uL
Hersteller ProSci
Menge 100 uL
Quantity options 100 uL
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
NCBI THRB
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias THRB,GRTH,PRTH,THR1,ERBA2,NR1A2,THRB1,THRB2,C-ERBA-2,C-ERBA-BETA
Versandbedingung Gekühlt
Lieferbar
Specificity Human,Mouse,Rat
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight
Observed: 53kDa
Manufacturer - Research Area
Cell Cycle, Growth Factors, Neuroscience, Signal Transduction, Transcription
Background
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.
By Type
Cell Cycle, Growth Factors, Neuroscience, Signal Transduction, Transcription
Modifications
None
Purification
Affinity purification
Positive Control 1
HepG2
Positive Control 2
U-87MG
Positive Control 3
Mouse liver
Positive Control 4
Mouse eye
Positive Control 5
Rat liver
Positive Control 6
Rat eye
Concentration
batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note
WB: 1:500 - 1:2000
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human THRB (NP_000452.2).
Clonality
Polyclonal
NCBI Official Name
thyroid hormone receptor, beta
NCBI Organism
Homo sapiens
User Note
Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
lieferbar

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