FLNA Antibody

ArtNr	PRS-16-580-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Antibodies Cell Biology Cell Movement Immunohistochemistry Western Blot Immunofluorescence Cardiovascular Research Thrombosis & Hemostasis Atherosclerosis Primary Antibodies Cell Migration & Invasion
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	FLNA
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	FLNA,filamin A,alpha,ABP-280,ABPX,CVD1,FLN,FLN-A,FLN1,FMD,MNS,NHBP,OPD,OPD1,OPD2,XLVD,XMVD,actin binding protein 280,alpha-filamin,endothelial actin-binding protein,filamin-1,filamin-A,non-muscle filamin
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 300kDa
Manufacturer - Research Area	Cell Cycle, Signal Transduction
Background	The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
By Type	Cell Cycle, Signal Transduction
Modifications	None
Purification	Affinity purification
Positive Control 1	Jurkat
Positive Control 2	HeLa
Positive Control 3	NIH/3T3
Positive Control 4	293T
Positive Control 5	U-251MG
Positive Control 6	Mouse lung
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IF: 1:50 - 1:200
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 2500 to the C-terminus of human FLNA (NP_001104026.1).
Clonality	Polyclonal
NCBI Official Name	filamin A, alpha
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 uL

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Lieferung vsl. bis 04.12.2025

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