PDE3A Antibody

ArtNr	PRS-18-159-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Antibodies Immunohistochemistry Western Blot Immunofluorescence Cardiovascular Research Thrombosis & Hemostasis Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	PDE3A
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PDE3A,CGI-PDE-A,HcGIP2,Phosphodiesterase 3a,Phosphodiesterase isoform 3a,CGI-PDE,CGI-PDE A,CGIP2,HPDE-3A,Phosphodiesterase type 3A
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 125kDa
Manufacturer - Research Area	Signal Transduction
Background	This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
By Type	Signal Transduction
Modifications	None
Purification	Affinity purification
Positive Control 1	HepG2
Positive Control 2	Mouse lung
Positive Control 3	Mouse heart
Positive Control 4	Mouse brain
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IHC: 1:50 - 1:100 IF: 1:50 - 1:100
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 380-660 of human PDE3A (NP_000912.3).
Clonality	Polyclonal
NCBI Official Name	phosphodiesterase 3A, cGMP-inhibited
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 100 uL

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Lieferung vsl. bis 04.12.2025

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