BAK1 Antibody, KO Validated

Blue Ice

Observed: 25kDa

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

KO

Affinity purification

HeLa

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

A synthetic peptide of human BAK1

BCL2-antagonist/killer 1

Optimal dilutions for each application to be determined by the researcher.