CNTF Antibody

Blue Ice

Observed: 26kDa

The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.

None

Mouse skeletal muscle

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CNTF (NP_000605.1).

ciliary neurotrophic factor

Optimal dilutions for each application to be determined by the researcher.