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PRDX2 Antibody, KO Validated

ArtNr PRS-18-385-100uL
Hersteller ProSci
Menge 100 uL
Quantity options 100 uL
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB, IF
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
NCBI PRDX2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias PRDX2,peroxiredoxin 2,HGNC:9353,MGC4104,NKEFB,PRP,PRXII,TDPX1,TSA,natural killer-enhancing factor B,thiol-specific antioxidant 1,thioredoxin peroxidase 1,thioredoxin-dependent peroxide reductase 1,torin
Versandbedingung Gekühlt
Lieferbar
Specificity Human,Mouse
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight
Observed: 20kDa
Manufacturer - Research Area
Cancer, Cell Cycle, Neuroscience
Background
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.
By Type
Cancer, Cell Cycle, Neuroscience
Badges
KO
Modifications
None
Purification
Affinity purification
Validation
Antibody is Knockout validated.
Positive Control 1
SW480
Positive Control 2
22Rv1
Positive Control 3
HepG2
Positive Control 4
K-562
Positive Control 5
BT-474
Positive Control 6
Mouse brain
Concentration
batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note
WB: 1:500 - 1:2000
IF: 1:50 - 1:200
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human PRDX2 (NP_859428.1).
Clonality
Polyclonal
NCBI Official Name
peroxiredoxin 2
NCBI Organism
Homo sapiens
User Note
Optimal dilutions for each application to be determined by the researcher.
Validation
Antibody is Knockout validated.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
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