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MMP9 Antibody, KO Validated

MMP9 Antibody, KO Validated

ArtNr	PRS-18-496-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Oncology Neuroscience Neuroinflammation Antibodies Western Blot Immunofluorescence Cardiovascular Research Atherosclerosis Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	MMP9
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MMP9 Antibody: GELB,CLG4B,MMP-9,MANDP2,Matrix metalloproteinase-9,92 kDa gelatinase
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 110kDa
Manufacturer - Research Area	Apoptosis, Cancer, Cell Cycle, Signal Transduction
Background	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
By Type	Apoptosis, Cancer, Cell Cycle, Signal Transduction
Badges	KO
Modifications	None
Purification	Affinity purification
Validation	Antibody is Knockout validated.
Positive Control 1	B-cell
Positive Control 2	MCF7
Positive Control 3	K-562
Positive Control 4	SW480
Positive Control 5	Mouse liver
Positive Control 6	Mouse lung
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IF: 1:50 - 1:200
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 538-707 of human MMP9 (NP_004985.2).
Clonality	Polyclonal
NCBI Official Name	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.
Validation	Antibody is Knockout validated.

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Menge: 100 uL

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