Vergleich

PDGFR beta Antibody

ArtNr PRS-18-555-100uL
Hersteller ProSci
Menge 100 uL
Quantity options 100 uL
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB, IF, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
NCBI PDGFRB
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias PDGFRB,CD140B,Beta pdfgr,Beta type PDGFR,BPDGFR,CD140b antigen,IBGC4,JTK12,PDGF-beta R,PDGF-R-beta,PDGFR,PDGFRbeta,PDGF receptor beta,PDGF-R,PDGFbetaR,PDGFR Beta,PDGFR-1,PDGFR-beta,BetaPDGFR,Pdgf beta-receptor,PDGFR1,PDGFRB/CEV14 fusion gene
Versandbedingung Gekühlt
Lieferbar
Specificity Human,Mouse,Rat
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight
Observed: 200kDa
Manufacturer - Research Area
Cancer, Cell Cycle, Growth Factors, Immunology, Signal Transduction
Background
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
By Type
Cancer, Cell Cycle, Growth Factors, Immunology, Signal Transduction
Modifications
None
Purification
Affinity purification
Positive Control 1
SH-SY5Y
Positive Control 2
Mouse lung
Positive Control 3
NIH/3T3
Positive Control 4
C2C12
Concentration
batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 887-1106 of human PDGFR beta (NP_002600.1).
Clonality
Polyclonal
NCBI Official Name
platelet-derived growth factor receptor, beta polypeptide
NCBI Organism
Homo sapiens
User Note
Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
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