PLCG2 Antibody

ArtNr	PRS-18-557-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Oncology Metabolism Cholesterol & Lipid Metabolism Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Immunohistochemistry Western Blot Immunofluorescence Cardiovascular Research Thrombosis & Hemostasis Enzymes Other Fatty Acid Enzymes Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	PLCG2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PLCG2,FCAS3,Phospholipase C-gamma-2,PLCG 2,PLC-IV,APLAID,Phospholipase C-IV,PLC-gamma-2
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 175kDa
Manufacturer - Research Area	Cancer, Cell Cycle, Immunology, Signal Transduction
Background	The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4, 5-bisphosphate to 1D-myo-inositol 1, 4, 5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
By Type	Cancer, Cell Cycle, Immunology, Signal Transduction
Modifications	None
Purification	Affinity purification
Positive Control 1	U-251MG
Positive Control 2	Raji
Positive Control 3	Ramos
Positive Control 4	HeLa
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IF: 1:20 - 1:100
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PLCG2 (NP_002652.2).
Clonality	Polyclonal
NCBI Official Name	phospholipase C, gamma 2 (phosphatidylinositol-specific)
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 100 uL

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Lieferung vsl. bis 04.12.2025

Express-Lieferung: 22 Tage sparen

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