MRE11A Antibody

Blue Ice

Observed: 90kDa-100kDa

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

None

Raji

U-937

A-375

batch dependent

WB: 1:500 - 1:2000
IF: 1:50 - 1:200
IP: 1:50 - 1:100

Polyclonal

Homo sapiens