ACTL6A Antibody

ArtNr	PRS-19-632-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Oncology Antibodies By Cell Type Carcinoma Western Blot Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	ACTL6A
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ACTL6,ARPN-BETA,Arp4,BAF53A,INO80K,actin-like protein 6A,53 kDa BRG1-associated factor A,BAF complex 53 kDa subunit,BAF53,BRG1-associated factor 53A,INO80 complex subunit K,actin-related protein 4,actin-related protein Baf53a,arpNbeta,hArpN beta
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 48kDa
Manufacturer - Research Area	Cell Cycle, Signal Transduction
Background	This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
By Type	Cell Cycle, Signal Transduction
Modifications	None
Purification	Affinity purification
Positive Control 1	HT-29
Positive Control 2	K-562
Positive Control 3	MCF7
Positive Control 4	BT-474
Positive Control 5	Mouse spleen
Positive Control 6	Mouse testis
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ACTL6A (NP_004292.1).
Clonality	Polyclonal
NCBI Official Name	actin like 6A
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 100 uL

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