RANTES Antibody

ArtNr	PRS-19-765-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Neuroscience Neuroinflammation Antibodies Western Blot Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	CCL5
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CCL5,Chemokine (C-C motif) ligand 5,D17S136E,EoCP,T-cell specific protein p288,SCYA5,SISd,T cell-specific protein P228,Beta-chemokine RANTES,C-C motif chemokine 5,RANTES,SIS-delta,Small-inducible cytokine A5,T-cell-specific protein RANTES,TCP228
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 13kDa
Manufacturer - Research Area	Chemokines & Cytokines, Immunology, Innate Immunity, Neuroscience
Background	This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms.
By Type	Chemokines & Cytokines, Immunology, Innate Immunity, Neuroscience
Modifications	None
Purification	Affinity purification
Positive Control 1	U-87MG
Positive Control 2	THP-1
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 24-91 of human RANTES (NP_002976.2).
Clonality	Polyclonal
NCBI Official Name	chemokine (C-C motif) ligand 5
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 100 uL

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Lieferung vsl. bis 04.12.2025

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