C8orf4 Antibody

Primary Antibodies

Store at -20˚ C. Avoid freeze / thaw cycles.

This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.

None

batch dependent

WB: 1:500 - 1:2000
IHC: 1:50 - 1:200

Polyclonal

Homo sapiens