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GLI2 Antibody

ArtNr PRS-22-276-100uL
Hersteller ProSci
Menge 100 uL
Quantity options 100 uL
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB
Specific against Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
NCBI GLI2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias zinc finger protein GLI2,Tax helper protein
Versandbedingung Gekühlt
Lieferbar
Specificity Mouse,Rat
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight
Observed: 90kDa
Manufacturer - Research Area
Cell Cycle, Neuroscience, Signal Transduction, Stem Cell, Transcription
Background
This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.
By Type
Cell Cycle, Neuroscience, Signal Transduction, Stem Cell, Transcription
Modifications
None
Purification
Affinity purification
Positive Control 1
Mouse lung
Positive Control 2
Mouse brain
Positive Control 3
Mouse heart
Positive Control 4
Mouse ovary
Positive Control 5
Mouse pancreas
Positive Control 6
Rat brain
Concentration
batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note
WB: 1:500 - 1:2000
Immunogen
Recombinant protein of mouse GLI2
Clonality
Polyclonal
NCBI Official Name
GLI-Kruppel family member GLI2
NCBI Organism
Mus musculus
User Note
Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
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