Acetyl-Histone H3-K18 pAb

Primary Antibodies

Blue Ice

Observed: 16kDa

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.

Acetylated

BT-474

H3

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

A synthetic acetylated peptide corresponding to residues surrounding K18 of human H3

histone cluster 1, H3d

Optimal dilutions for each application to be determined by the researcher.