TNFRSF8 Antibody

Blue Ice

Observed: 128kDa

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

None

HeLa

H460

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

A synthetic peptide of human TNFRSF8

tumor necrosis factor receptor superfamily, member 8

Optimal dilutions for each application to be determined by the researcher.