DPM1 Antibody

ArtNr	PRS-23-161-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Metabolism Cholesterol & Lipid Metabolism Antibodies Western Blot Immunofluorescence Enzymes Prostaglandin Synthases Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	DPM1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DPM1,dolichyl-phosphate mannosyltransferase polypeptide 1,catalytic subunit,CDGIE,MPDS,dolichol monophosphate mannose synthase
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 30kDa
Manufacturer - Research Area	Other
Background	Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants.
By Type	Other
Modifications	None
Purification	Affinity purification
Positive Control 1	NCI-H460
Positive Control 2	HeLa
Positive Control 3	SKOV3
Positive Control 4	Mouse pancreas
Positive Control 5	Mouse liver
Positive Control 6	Mouse kidney
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IF: 1:50 - 1:200
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DPM1 (NP_003850.1).
Clonality	Polyclonal
NCBI Official Name	dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 100 uL

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Lieferung vsl. bis 01.01.2026

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