PDE6A Antibody

ArtNr	PRS-23-277-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Neuroscience Metabolism Diabetes Molecular Targets for Neuroscience Neural Development Antibodies Immunohistochemistry Western Blot Cardiovascular Research Thrombosis & Hemostasis Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	PDE6A
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PDE6A,Alpha-PDE,CGMP phosphodiesterase alpha,CGPR-A,PDE6alpha,PDE V-B1,PDEA,Phosphodiesterase 6a,RP43,GMP-PDE alpha
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 120kDa
Manufacturer - Research Area	Neuroscience, Signal Transduction
Background	This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
By Type	Neuroscience, Signal Transduction
Modifications	None
Purification	Affinity purification
Positive Control 1	BT-474
Positive Control 2	Rat brain
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IHC: 1:50 - 1:200
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 656-860 of human PDE6A (NP_000431.2).
Clonality	Polyclonal
NCBI Official Name	phosphodiesterase 6A, cGMP-specific, rod, alpha
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 100 uL

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Lieferung vsl. bis 01.01.2026

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