ARHGEF11 Antibody

Blue Ice

Observed: 168kDa

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described.

None

Mouse brain

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

A synthetic peptide of human ARHGEF11

Rho guanine nucleotide exchange factor (GEF) 11

Optimal dilutions for each application to be determined by the researcher.