PER1 Antibody

ArtNr	PRS-23-592-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Neuroscience Metabolism Regulation of Appetite Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	PER1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Period circadian protein homolog 1,hPER1,Circadian clock protein PERIOD 1,Circadian pacemaker protein Rigui,PER1,KIAA0482,PER,RIGUI
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 160kDa
Manufacturer - Research Area	Neuroscience, Transcription
Background	This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described.
By Type	Neuroscience, Transcription
Modifications	None
Purification	Affinity purification
Positive Control 1	Jurkat
Positive Control 2	B cells
Positive Control 3	A-549
Positive Control 4	Mouse brain
Positive Control 5	Mouse testis
Positive Control 6	Rat brain
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IHC: 1:50 - 1:100 IF: 1:50 - 1:200
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PER1 (NP_002607.2).
Clonality	Polyclonal
NCBI Official Name	Period circadian protein homolog 1
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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