RNF34 Antibody

ArtNr	PRS-23-634-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Neuroscience Metabolism Diabetes Glucose Homeostasis Targets for Rodent Neurosciences Antibodies Cell Biology Cytoskeleton Western Blot Primary Antibodies small GTPases Arf Subfamily
Typ	Antibody Primary
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	RNF34
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	RNF34,ring finger protein 34,RFI,RIF,RIFF,FLJ21786,RING finger protein RIFF,FYVE-RING finger protein MOMO,hRFI,CARP1,CARP-1
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 42kDa
Manufacturer - Research Area	Apoptosis, Cell Cycle
Background	The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms.
By Type	Apoptosis, Cell Cycle
Modifications	None
Purification	Affinity purification
Positive Control 1	U-251MG
Positive Control 2	LO2
Positive Control 3	HeLa
Positive Control 4	BT-474
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human RNF34 (NP_079402.2).
Clonality	Polyclonal
NCBI Official Name	ring finger protein 34, E3 ubiquitin protein ligase
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 100 uL

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Lieferung vsl. bis 06.11.2025

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