Antibodies

Rabbit anti-PIK3C3/hVPS34 [+Biotin]

Hersteller Raybiotech
Kategorie
Typ Antibody
Specific against Human
Isotype IgG
Format Supplied as 200 ug of purified and lyophilized antibody. The antibody is stable for at least one year from the date of receipt when stored at -20C to -70C. Reconstituted antibody (suggesting with sterile PBS containing 0.1% BSA) can also be aliquotted and
Applikationen ELISA
Menge 50 ug
Host Rabbit
ArtNr RB-08-0037B-50
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Target Name
PIK3C3/hVPS34
Accession Number
NM_002647.2
Conjugate/Tag/Label
Biotin
Application notes:
ELISA (recommended work dilution= 1:32, 000 (Minimum detecting ability 30 ng/ml))
Product Description
The Class III PI3K (phosphoinositide 3-kinase), Vps34 (vacuolar protein sorting 34), was first identified in yeast, then it was also defined in mammalian cells of different species, including human, designated as hVPS34. Investigations shown that it could play an important role in the ability of cells to respond to changes in nutrient conditions. In both yeast and mammalian cells, Class III PI3Ks are also required for the induction of autophagy during nutrient deprivation. Finally, mammalian hVPS34 is itself regulated by nutrients. Thus Class III PI3Ks are implicated in the regulation of both autophagy and, through the mTOR pathway, protein synthesis, and thus contribute to the integration of cellular responses to changing nutritional status.
Immunogen
Immunogen was synthetic peptide derived from Human hVPS34. This antibody was produced from a rabbit immunized with the immunogen. The IgG fraction was purified from rabbit serum by ammonium sulphate precipitation followed by Protein A/G affinity chromatography.

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Menge: 50 ug
Lieferbar: In stock
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